产品货号：
Z33393
中文名称：
ATM抗体
英文名称：
Anti-ATM Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATM Antibody |
| 指标别名 | A T mutated;AT1;ATA;ataxia telangiectasia mutated;ATC;ATD;ATDC;ATE;ATM;Serine protein kinase ATM;TEL1;TELO1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF |
| 基因名称 | ATM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human ATM |
| 实际分子量 | 350KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ATM(ataxia telangiectasia mutated),also known as TEL1 or TELO1,is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks.The ATM protein is a member of the phosphatidylinositol 3-kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control.The ATM gene is mapped to chromosome 11q22.3.ATM has an essential role in the reconstitutive capacity of hematopoietic stem cells but is not as important for the proliferation or differentiation of progenitors in a telomere-independent manner.ATM functions directly in the repair of chromosomal DNA double-stranded breaks by maintaining DNA ends in repair complexes generated during lymphocyte gene assembly. |
| Uniprot ID | Q13315 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
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